Based on a Century of Scientific Research

Ketosis is a well-understood physiologic process with proven therapeutic benefits, which has existed in medical literature for over 100 years.

The Mayo Clinic ran the first clinical trial on the keto diet in 1921; studying the effects it had on epileptic children. The results of their research suggest promising results for reducing seizures and easing other symptoms of the disease when entering a state of ketosis.

Below is a small collection of some of the most important and informative research papers to help support your understanding of the proven science behind Keto5.

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Ketogenic Diets and Exercise Performance

The ketogenic diet (KD) has gained a resurgence in popularity due to its purported reputation for fighting obesity. The KD has also acquired attention as an alternative and/or supplemental method for producing energy in the form of ketone bodies.

Effects of a low carbohydrate weight loss diet on exercise capacity and tolerance in obese subjects

Dietary restriction and increased physical activity are recommended for obesity treatment. Very low carbohydrate diets are used to promote weight loss, but their effects on physical function and exercise tolerance in overweight and obese individuals are largely unknown. The aim of this study was to compare the effects of a very low carbohydrate, high fat (LC) diet with a conventional high carbohydrate, low fat (HC) diet on aerobic capacity, fuel utilization during submaximal exercise, perceived exercise effort (RPE) and muscle strength.

Efficacy of low carbohydrate and ketogenic diets in treating mood and anxiety disorders: systematic review and implications for clinical practice

The article discusses the growing interest in the use of low and very low carbohydrate ketogenic diets for treating neurological and psychiatric conditions. The potential efficacy of these diets for various disorders is being studied and explored.

Effects of energy-restricted high-protein, low-fat compared with standard-protein, low-fat diets: a meta-analysis of randomized controlled trials

The objective was to conduct a systematic review and meta-analysis of studies that compared energy-restricted, isocaloric, high-protein, low-fat (HP) diets with standard-protein, low-fat (SP) diets on weight loss, body composition, resting energy expenditure (REE), satiety and appetite, and cardiometabolic risk factors.

Prevalence of childhood and adult obesity in the United States, 2011-2012

To provide the most recent national estimates of childhood obesity, analyze trends in childhood obesity between 2003 and 2012, and provide detailed obesity trend analyses among adults.

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Based on a Century of Scientific Research

Ketogenic Diets and Exercise Performance

Effects of a low carbohydrate weight loss diet on exercise capacity and tolerance in obese subjects

Efficacy of low carbohydrate and ketogenic diets in treating mood and anxiety disorders: systematic review and implications for clinical practice

Effects of energy-restricted high-protein, low-fat compared with standard-protein, low-fat diets: a meta-analysis of randomized controlled trials

Prevalence of childhood and adult obesity in the United States, 2011-2012

Prevalence of childhood and adult obesity in the United States, 2011-2012

Effects of energy-restricted high-protein, low-fat compared with standard-protein, low-fat diets: a meta-analysis of randomized controlled trials

Efficacy of low carbohydrate and ketogenic diets in treating mood and anxiety disorders: systematic review and implications for clinical practice

Effects of a low carbohydrate weight loss diet on exercise capacity and tolerance in obese subjects

Ketogenic Diets and Exercise Performance

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