This study compared the effect of a hypocaloric ketogenic diet (KD) with or without ketone supplementation (KS) and a low-fat diet (LFD) on liver fat reduction in overweight adults. The results showed that all diets significantly reduced liver fat, including in participants with nonalcoholic fatty liver disease (NAFLD), with no significant differences between the groups. The study suggests that both KDs and LFDs can be used to reduce liver fat in individuals with NAFLD.