Based on a Century of Scientific Research

Ketosis is a well-understood physiologic process with proven therapeutic benefits, which has existed in medical literature for over 100 years.

The Mayo Clinic ran the first clinical trial on the keto diet in 1921; studying the effects it had on epileptic children. The results of their research suggest promising results for reducing seizures and easing other symptoms of the disease when entering a state of ketosis.

Below is a small collection of some of the most important and informative research papers to help support your understanding of the proven science behind Keto5.

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The Three-Month Effects of a Ketogenic Diet on Body Composition, Blood Parameters, and Performance Metrics in CrossFit Trainees: A Pilot Study

A study was conducted to evaluate the effects of a 12-week ketogenic diet (KD) on body composition, metabolic, and performance parameters in individuals who trained recreationally at a local CrossFit facility. The results showed that the KD group experienced a significant reduction in body mass, body fat percentage, and body mass index, with no significant changes in muscle mass. Additionally, the KD group demonstrated significant improvements in endurance exercise performance, with no significant changes in strength performance.

Dietary R, S-1,3-butanediol diacetoacetate reduces body weight and adiposity in obese mice fed a high-fat diet

The study aimed to investigate whether R, S-1,3-butanediol diacetoacetate (BD-AcAc2), a ketone ester, increases energy expenditure and markers of adipose tissue thermogenesis in mice with HFD-induced obesity. The results showed that BD-AcAc2 increased resting energy expenditure and markers of brown and white adipose thermogenesis in obese mice, suggesting its potential as a therapeutic intervention for obesity.
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